NELL1 is a target antigen in malignancy-associated membranous nephropathy
نویسندگان
چکیده
منابع مشابه
Glomerular IgG subclasses in idiopathic and malignancy-associated membranous nephropathy
BACKGROUND In idiopathic membranous nephropathy (MN), antibodies directed towards the glomerular phospholipase A2 receptor (PLA2R) have mainly been reported to be of IgG4 subclass. However, the role of the different IgG subclasses in the pathogenesis of MN, both in idiopathic MN and in secondary cases, is still unclear. In this retrospective study, we test the hypothesis that the absence of glo...
متن کاملTherapy of membranous nephropathy associated with malignancy and secondary causes.
Membranous nephropathy (MN) most commonly is idiopathic, but secondary causes are common in children and in older adults. The most common secondary causes of MN in industrialized countries include malignancy and systemic lupus erythematosis. Infectious causes (hepatitis B, quartan malaria, schistosomiasis) remain the most common etiologies in endemic areas. In this article we describe the clini...
متن کاملMalignancy in Membranous Nephropathy: Evaluation of Incidence
BACKGROUND Membranous nephropathy (MN) can be associated with malignancy. However, the relative risk for malignancy remains unclear. It has been reported that higher numbers of inflammatory cells seen in the glomeruli at biopsy correlate with the occurrence of malignancy in patients with MN and might be used to direct screening. METHODS We examined the occurrence of malignancy in 201 MN patie...
متن کاملMembranous Nephropathy Associated with Atheroembolism
Membranous nephropathy (MN) is one of the most common biopsy diagnoses in adults, and it has been associated with chronic infections, autoimmune diseases, malignancies, and drugs. However, MN associated with cholesterol crystal emboli has never been reported. Here we present a patient with MN as an unusual manifestation of atheroembolism. A 75-year-old man with worsening renal function after ca...
متن کاملMembranous Nephropathy Associated with Tuberculosis
Correspondence To the Editor: Glomerulonephritis (GN) due to Mycobacterium tuberculosis (M. tuberculosis) is rare, [1] and membranous nephropathy (MN) associated with tuberculosis is seldom reported. Because of atypical and nonspecific manifestations, tuberculosis‑associated GN (TB‑GN) is difficult to diagnose. Patients usually present with hematuria, proteinuria, edema, and varying degrees of ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2021
ISSN: 0085-2538
DOI: 10.1016/j.kint.2020.07.039